Ganglioside Storage Disorders

《英文msh詞典》Ganglioside Storage Disorders
[入口詞] Ganglioside Storage Disorders
[主題詞] Gangliosidoses
[英文釋義] A group of often fatal inherited diseases marked by the accumulation of GANGLIOSIDES in LYSOSOMES secondary to enzymatic deficiency states. Gangliosidoses include TAY-SACHS DISEASE; GANGLIOSIDOSIS GM1; GANGLIOSIDOSES GM2; and SANDHOFF DISEASE; which share the infantile or childhood onset of CENTRAL NERVOUS SYSTEM deterioration. (Menkes,Textbook of Child Neurology,5th ed,pp89-97)